Kemri NGO Jobs.Senior Clinical Officer – CHAIN Study



JOB PURPOSE:This role will involve the day to day clinical care and responsibility for a cohort study at Kilifi County Hospital. The post holder conducts daily activities to ensure clinical assessment and care, timely recruitment, data collection in hospital and during community follow up, effective communication with participants and adherence to study-specific procedures in the CHAIN study and related malnutrition studies. The post holder will also be key contact person for communication with clinical team in the ward regarding the study.



Principal Investigator, through the study coordinator


Head of clinical services


Helps supervise nursing and fieldworker team


The KEMRI-Wellcome Trust Research Programme conducts high quality clinical trials focussing on diseases that present a high burden for developing countries.

CHAIN study is a large multi-site cohort study under Childhood Acute Illness and Nutrition Network (CHAIN Network) that aims to build the evidence-base for the care of sick and undernourished children in resource-limited settings. CHAIN Network brings together clinicians and scientists from a wide variety of high disease-burden settings in Africa and South Asia, to create a set of systematically collected data and samples harmonized between sites that are generalizable, optimal for pooled analyses, and allow for comparisons between and across sites. To meet this goal, the CHAIN Network is conducting studies to identify clinical, social and behavioral characteristics of children at risk of death during and after hospitalization.

The post holder will have a high level of responsibility for ensuring study integrity, adherence to standard procedures, managing staff and ensuring that the study runs smoothly. The post holder will need to be self-sufficient and be able to work unsupervised, often with an unpredictable timescale. The post is mentally demanding, and involves a high level of communication among study staff, study participants, and the wider community.

Staff operating at this grade range contribute to a research team and deal with non-standard work situations more regularly than staff at lower grades and take decisions often relating to the interpretation of standard operating procedures.  They are required to provide guidance to team members at lower grades, and also be involved in supervising the work of others. Staff have responsibility for prioritising their own work and ensuring the necessary equipment/materials are available.


  • Take on lead role amongst clinical staff at the hospital in planning and implementing participant recruitment for CHAIN study at the site and ensure complete data collection according to study protocol.
  • Examine and evaluate patients, diagnose and treat ailments, particularly in children in the CHAIN study cohort
  • Review of patients and make relevant changes or amendments to care and liaise with the senior clinicians on call as may be necessary.
  • To be the key clinical contact on treatment and care of children with enrolled into CHAIN study, facilitating trainings and CME in the subject area of undernutrition.
  • Continuously oversee and review best practice by other clinicians related to care and treatment of children with undernutrition and be involved in research activities in malnutrition
  • Screen and identify potentially eligible participants among paediatric admissions for CHAIN study and other malnutrition studies.
  • Provide information, education and support to families or guardians of potentially eligible research subjects.
  • Administer and oversee the informed consent process.
  • Conduct study-related assessments and collection of data using case record forms in accordance to Good Clinical Practice (GCP).
  • Assist with documentation and reporting of adverse events and clinical endpoints, including death and readmission to hospital.
  • Prepare and submit regular progress study reports for the site for use during routine update meetings.
  • Ensure that the whole study teams are working according to GCP and research governance standards for clinical research
  • Be required to undertake other duties, which are broadly in line with the above key roles and responsibilities.



  • Diploma in Clinical Medicine
  • Higher National Diploma in Paediatrics and Child health or equivalent
  • Registered by the Kenya Clinical Officers Council
  • At least 6 years clinical experience in paediatric care
  • Knowledge of Good Clinical Practice in research studies
  • Knowledge/ experience in organisation of research studies
  • Flexible – able to work extra hours when needed
  • Able work under stressful environment, self-driven and highly motivated
  • Strong interpersonal and communication skills (oral and written)
  • Personnel management skills and computer-literate with proficiency in project management tools and Microsoft applications


  • Experience of clinical trials work
  • Experience of care for sick, malnourished children


  • Based at Kilifi County Hospital.
  • Be available to work flexibly, out of hours as necessary.
  • Exposure to patients and materials considered infectious and/or biohazards.